abstract：:The present study was addressed to determine whether the high expression of peroxisome proliferator-activated receptor-alpha (PPAR-alpha) in rat liver during the perinatal stage plays a role in the induction of liver lipoprotein lipase (LPL) expression and activity. Parallel increases in liver mRNA PPAR-alpha and LPL ...

journal_title：Journal of physiology and biochemistry

authors： Panadero M,Bocos C,Herrera E

更新日期：2006-09-01 00:00:00

abstract：:Adiponectin, a hormone produced by adipocytes, is involved in glucose metabolism and insulin sensitivity. The production of this adipokine is impaired in obesity and insulin resistance. Eicosapentaenoic acid (EPA) is a dietary n-3 polyunsaturated fatty acid that improves insulin sensitivity in several models of obesit...

journal_title：Journal of physiology and biochemistry

authors： Lorente-Cebrián S,Pérez-Matute P,Martínez JA,Marti A,Moreno-Aliaga MJ

更新日期：2006-06-01 00:00:00

abstract：:In the absence of progesterone (P), the anti-P at the receptor RU486 reduces basal and GnRH-stimulated LH secretion both in vivo and in vitro, demonstrating the existence of a ligand-independent activation of progesterone receptor (LIAPR). The aim of the present study was to determine which component of the intracellu...

journal_title：Journal of physiology and biochemistry

authors： Garrido-Gracia JC,Bellido C,Aguilar R,Sánchez-Criado JE

更新日期：2006-03-01 00:00:00

abstract：:GLUT2 is a facilitative glucose transporter located in the plasma membrane of the liver, pancreatic, intestinal, kidney cells as well as in the portal and the hypothalamus areas. Due to its low affinity and high capacity, GLUT2 transports dietary sugars, glucose, fructose and galactose in a large range of physiologica...

journal_title：Journal of physiology and biochemistry

authors： Leturque A,Brot-Laroche E,Le Gall M,Stolarczyk E,Tobin V

更新日期：2005-12-01 00:00:00

abstract：:Chronic renal disease is characterized by the accumulation of extracellular matrix proteins in the kidney and a loss of renal function. Tubulointerstitial fibrosis has been reported to play an important role in the progression of chronic renal diseases. Transforming growth factor-beta1 (TGF-beta1) is a profibrotic cyt...

journal_title：Journal of physiology and biochemistry

authors： Prieto M,Rodríguez-Peña AB,Düwel A,Rivas JV,Docherty N,Pérez-Barriocanal F,Arévalo M,Vary CP,Bernabeu C,López-Novoa JM,Eleno N

更新日期：2005-09-01 00:00:00

abstract：:In pregnancy there occurs maternal tolerance to the foetus. Several mechanisms have been proposed to explain this phenomenon. The main immune population in the decidua are macrophages and natural killer cells, but with some "special" suppressor characteristics. There is also a predominant TH2 response. The non classic...

journal_title：Journal of physiology and biochemistry

authors： González A,López AS,Alegre E,Alcázar JL,López-Moratalla N

更新日期：2004-09-01 00:00:00

abstract：:In order to transform cytosolic fructose-1,6-bisphosphatases (FBPase)(EC 3.1.3.11) into potential reductively-modulated chloroplast-type enzymes, we have constructed four chimeric FBPases, which display structural viability as deduced by previous modelling. In the X1-type BV1 and HL1 chimera the N-half of cytosolic su...

journal_title：Journal of physiology and biochemistry

authors： Cazalis R,Chueca A,Sahrawy M,López-Gorgé J

更新日期：2004-03-01 00:00:00

abstract：:We examined the serum concentrations of leptin in a homogeneous group of 52 postmenopausal Mediterranean women, calculating body fat mass distribution by waist-to-hip circumference ratio (WHR) and other anthropometric measurements. Significant correlations were found between leptin and weight (r=0.59), Body Mass Index...

journal_title：Journal of physiology and biochemistry

authors： Martínez-Carpio PA,Fiol C,Hurtado I,Arias C,Ruiz E,Orozco P,Corominas A

更新日期：2003-12-01 00:00:00

abstract：:Conjugated linoleic acid (CLA) refers to a mixture of naturally occurring positional and geometric isomers of linoleic acid that exist in dairy products and meat. The aim of the present work was to study the effects of c-9,t-11 and t-10,c-12 CLA isomers on body fat accumulation and serum lipids in hamsters fed an athe...

journal_title：Journal of physiology and biochemistry

authors： Navarro V,Zabala A,Macarulla MT,Fernández-Quintela A,Rodríguez VM,Simón E,Portillo MP

更新日期：2003-09-01 00:00:00

abstract：:The number of patients that suffer some type of spinal cord lesion in recent years are high and have increased because of factors such as traffic accidents. Although their life expectancy has increased, cardiovascular illnesses is one of the main causes of morbidity and mortality. Since the degree of physical fitness ...

journal_title：Journal of physiology and biochemistry

authors： Vidal J,Javierre C,Segura R,Lizarraga A,Barbany JR,Pérez A

更新日期：2003-03-01 00:00:00

abstract：:Growth hormone plays a key role in the maturation and maintenance of the immune response, however, the effects of chronic high circulating concentrations of the hormone on the immune system is poorly understood. Transgenic mice overexpressing bovine growth hormone (b-GH) gene, fused to the rat phosphoenolpyruvate carb...

journal_title：Journal of physiology and biochemistry

authors： Esquifino AI,Arce A,Alvarez MP,Szary A,Brown-Borg H,Bartke A

更新日期：2002-09-01 00:00:00

abstract：:Platelets play an essential role in primary hemostasis and in thrombotic events, particularly in arterial vessels, as rheological conditions originate closer interactions between platelets and endothelium than lower shear rates. In response to vascular injury, platelets adhere to the subendothelial matrix by membrane ...

journal_title：Journal of physiology and biochemistry

authors： Rivera J,Lozano ML,Corral J,González-Conejero R,Martínez C,Vicente V

更新日期：2000-12-01 00:00:00

abstract：:There are a number of hypothetical explanations for the actions of ethanol on the exocrine pancreas; among them, the cholinergic hypothesis has received special attention. According to this hypothesis, chronic alcohol consumption induces alterations in the control of exocrine pancreatic function resulting in cholinerg...

journal_title：Journal of physiology and biochemistry

authors： Acosta JJ,San Román JI,López MA,Calvo JJ

更新日期：2000-09-01 00:00:00

abstract：:In order to obtain healthier goat milk as far as its fat composition is concerned, milk production and composition trials were carried out with Granadina goats kept in semi-extensive breeding conditions. The animals were feeding indoors with a concentrate supplemented or not with 7% of fat conveniently protected again...

journal_title：Journal of physiology and biochemistry

authors： Sanz Sampelayo MR,Martín Alonso JJ,Morón D,Pérez L,Boza J

更新日期：2000-09-01 00:00:00

abstract：:Two groups of rats were fed on diets with protein from a marine specie holothuria (Holothuria forskali) or casein (for the control group) during 16 days with the aim of assessing the nutritional value of the holothuria protein. Several serum lipid levels were also determined. The results of the nutritive parameters in...

journal_title：Journal of physiology and biochemistry

authors： Rodríguez E,González M,Caride B,Lamas MA,Taboada MC

更新日期：2000-03-01 00:00:00

abstract：:Variations in the concentration of free amino acids in the muscle and plasma of trout submitted to 5 minutes of intense exercise have been studied. The responses of untrained fish and those trained performing the same type of exercise twice daily for 28 days are compared. Total amino acid concentrations in muscle tend...

journal_title：Journal of physiology and biochemistry

authors： Marín JF,Mendiola P,Hernández MD,De Costa J,Zamora S

更新日期：1999-12-01 00:00:00

abstract：:O-Acetylserine(thiol)lyase (OASTL) enzyme catalyzes the cysteine biosynthesis in photosynthetic organisms. In mature Arabidopsis thaliana the highest activity level is observed in non-photosynthetic tissues like roots, that also show significant amount of protein detected by Western blot analysis. By means of specific...

journal_title：Journal of physiology and biochemistry

authors： Barroso C,Vega JM,Gotor C

更新日期：1998-12-01 00:00:00

abstract：:Total level of O-acetyl-L-serine(thiol)lyase (OASTL) activity observed in Monoraphidium braunii fed-repleted cells decreases up to 40% after 24 h the carbon source was removed from the culture; however, no significant change in the activity is observed in N-starved cells. On the other hand, sulfur starvation induces O...

journal_title：Journal of physiology and biochemistry

authors： González-Arroyo JG,Vega JM,Pérez-Castiñeira JR

更新日期：1998-09-01 00:00:00

abstract：:To investigate the effects of pectin on cholesterol metabolism, normal rats were fed for three weeks a diet containing 2.5 or 5 % apple or orange pectin, or without pectin (control). Cholesterol concentrations were determined in faeces after 1, 2 and 3 weeks of treatment, and in liver and serum at the end of the exper...

journal_title：Journal of physiology and biochemistry

authors： González M,Rivas C,Caride B,Lamas MA,Taboada MC

更新日期：1998-06-01 00:00:00